1 B Roy & BR Giri.pmd
نویسندگان
چکیده
The current study was carried out to test the root hair extract of Carex baccans, a traditionally used medicinal plant by the natives (Jaintia tribes) of Northeast India, for its anthelmintic efficacy on the trematode Artyfechinostomum sufrartyfex. The test parasites were exposed to different concentrations of the root hair extract of the plant and praziquantel, a broad-spectrum anthelmintic at 37±1°C. Control parasites were incubated in PBS only. Immediately after attaining paralysis, the parasites were processed for histochemical analysis. Motility and mortality data obtained from the study showed a positive dose dependent relationship. A significant reduction in acetylcholinesterase activity in the parasites treated with different concentration of plant extract was observed compared to control parasites. Considerable inhibitions in the acetylcholinesterase activity in the treated parasites are suggestive of an efficient vermicidal activity of the root hair extract of C. baccans against A. sufrartyfex.
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